Cancun (CUN) is one of the most popular US–Mexico routes, with dozens of nonstop flights daily from cities across the USA including New York, Miami, Dallas, Chicago, Atlanta, Los Angeles, and Houston. American Airlines, United, Delta, Southwest, JetBlue, Aeromexico, Viva Aerobus, Frontier, and Volaris all serve Cancun. Flight times range from approximately 2h 30m (from Dallas or Houston) to 4h 30m (from New York or Los Angeles). Cancun is the gateway to the Riviera Maya, Tulum, Playa del Carmen, and Cozumel. Round-trip fares from New York average $350–$650 depending on season, with September and January offering the best deals.

Mexico City (MEX) is the most-served Mexican destination from the USA. Aeromexico, American Airlines, United, Delta, Volaris, and Viva Aerobus all offer nonstop service from multiple US hubs. Flight times range from approximately 2h 45m (Dallas) to 5h 15m (New York). Around 240 direct flights operate daily from US cities to Mexico City. Average round-trip fares from New York range from $350–$700 depending on season. Book 6–8 weeks ahead for the best prices.

For the best flight to Mexico City, Aeromexico offers the most nonstop options from the widest range of US cities, with Clase Premier business class on select routes. For budget travelers, Volaris and Viva Aerobus offer the lowest base fares from Los Angeles, Chicago, Dallas, and Houston. US travelers connecting through their home hub often find the best combination of price and convenience with American (DFW/MIA hub), United (IAH/ORD hub), or Delta (ATL hub).

Guadalajara (GDL) — the capital of Jalisco and gateway to tequila country — is well-served from the USA by Aeromexico, American Airlines, United, Delta, Volaris, and Viva Aerobus. Nonstop flights are available from Los Angeles, San Francisco, Dallas, Chicago, Houston, and New York, among other cities. Flight times range from approximately 2h 30m (from Los Angeles) to 4h 30m (from New York). Average round-trip fares from Los Angeles to Guadalajara range from $250–$450.

Flight cancellations to Mexico can occur for several reasons. In early 2026, significant cancellations across Guadalajara, Puerto Vallarta, and other western Mexican airports followed cartel-related security incidents, which prompted US airlines (including American, Southwest, United, Delta, and Alaska) to temporarily suspend or divert flights. Weather events — including tropical storms affecting Cancun and heavy rainy-season flooding at Mexico City's airport — also cause periodic disruptions. Operational pressures at low-cost Mexican carriers (Volaris, Viva Aerobus) due to thin scheduling and merger activity have caused additional delays. Always check your flight status before departure and monitor US State Department travel advisories for current conditions.

The major airlines flying to Mexico from the USA include Aeromexico, American Airlines, United Airlines, Delta Air Lines, Southwest Airlines, JetBlue, Alaska Airlines, Volaris, Viva Aerobus, and Frontier Airlines. Aeromexico operates the most extensive nonstop network, while US legacy carriers dominate high-frequency routes from major hubs. Budget carriers Volaris, Viva Aerobus, and Frontier offer the lowest base fares, particularly from western US cities. Together, these airlines operate nonstop flights from 61 US airports to 38 Mexican destinations.

Guanajuato is served by Del Bajío International Airport (BJX), located near the city of León. Aeromexico and Volaris offer nonstop flights from Los Angeles (LAX) and Houston (IAH/HOU). Flight time from Los Angeles to BJX is approximately 2h 45m. For travelers from the East Coast or Midwest, connections via Mexico City or Dallas are typically required. BJX is the ideal gateway for visiting the colonial cities of Guanajuato, San Miguel de Allende, and León.

There are no regular nonstop flights from Raleigh-Durham International Airport (RDU) to León (BJX). Travelers typically connect through Dallas–Fort Worth (DFW), Houston (IAH), Atlanta (ATL), or Mexico City (MEX) to reach León. American Airlines (via DFW or MIA), United (via IAH), and Delta (via ATL) offer convenient connections. Total journey time from Raleigh to León is approximately 6–8 hours depending on connection. Check Triwize for the best fares and connection options.

"Mexico DF" refers to Mexico City's historic designation as "Distrito Federal" (DF), before it was renamed CDMX (Ciudad de México) in 2016. Mexico City is served by two international airports: Benito Juárez International (MEX), the main hub, and the newer Felipe Ángeles International (NLU). Most US flights arrive at MEX, which is served by 30+ international airlines. If you see "Mexico DF" on a booking, it refers to Mexico City and typically routes through MEX.

San Francisco International Airport (SFO) offers nonstop flights to Mexico with multiple airlines. Aeromexico operates nonstop SFO–MEX (Mexico City) service, as does United Airlines and Volaris. For Cancun, nonstop service is available seasonally from SFO with select carriers; otherwise one-stop connections via LAX, DFW, or MEX are convenient. Flight time from SFO to Mexico City is approximately 4h 15m nonstop. Average round-trip fares from SFO to Mexico City range from $300–$600 depending on season.

Jalisco — Mexico's second-most-visited state — is served primarily through Guadalajara International Airport (GDL) and Puerto Vallarta International Airport (PVR). Both airports receive nonstop flights from major US cities. Guadalajara is the commercial and cultural capital of Jalisco, while Puerto Vallarta serves the Pacific coast resort region and the Riviera Nayarit. Los Angeles, Dallas, Chicago, Houston, Phoenix, and San Francisco all offer nonstop service to Guadalajara and/or Puerto Vallarta.

Guadalajara (GDL) is one of Mexico's most popular destinations for US travelers, particularly from California and Texas. Aeromexico, American Airlines, United, Delta, Volaris, Viva Aerobus, and Alaska Airlines all serve GDL from US cities including Los Angeles, San Francisco, Dallas, Houston, Chicago, and Phoenix. GDL is also a hub for Volaris, making it extremely well-connected domestically within Mexico. Nonstop flight times from Los Angeles are approximately 2h 30m; from New York, approximately 5h with a connection.

To find the best flight to Mexico today, search Triwize with flexible date options to compare same-day and next-day fares across 500+ airlines. For last-minute flights, routes from Texas (Dallas or Houston) to Mexico City or Monterrey tend to have the highest frequency and best last-minute availability. Setting a fare alert on Triwize for your preferred route is the most reliable way to catch the best available price. Remember to check US State Department travel advisories for your specific destination before booking.